S.E.M.I.: Side Effects May Include...
2026· Two Horn Unicorn· Hack and slash/Beat 'em up, Indie, Arcade · PC
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65%
Mixed 47 reviews
Premise via IGDB
S.E.M.I. is a cooperative online game about escaping from a special clinic. Here you and up to 3 of your feeble-minded loyal friends in the role of patients fight with the staff and other patients and find yourself in unexpected situations....
S.E.M.I. is a cooperative online game about escaping from a special clinic. Here you and up to 3 of your feeble-minded loyal friends in the role of patients fight with the staff and other patients and find yourself in unexpected situations. Teamwork is essential, as randomized events and experimental drugs will lead your party into unpredictable mayhem. Pop pills with your friends as you cooperate to gain your freedom.
Screenshots & Media
Game Details
Developer Two Horn Unicorn
Publisher Two Horn Unicorn
Release
Platforms PC (Microsoft Windows)
Engine Unreal Engine 5
Steam Deck Unknown
OS Support Windows
Game Modes Single player, Multiplayer, Co-operative
Steam Reviews Mixed (47)
ESRB E10+
PEGI 12
Chinese (Simplified): Audio, Interface
Dutch: Audio, Interface
English: Audio, Interface
English (UK): Audio, Interface
French: Audio, Interface
German: Interface
Japanese: Audio, Interface
Portuguese (Brazil): Audio, Interface
Russian: Audio, Interface
Spanish (Spain): Audio, Interface
Price History
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